ABSTRACT
Objective. Identify the scientific production published in journals indexed in the Scopus database on SARS-CoV-2, to quantify the scientific information available for the decision-making process of the relevant authorities. Design/Methodology/Approach. It is a documentary research, which uses bibliometric analysis of articles published in scientific journals indexed in the Scopus database, using EndNote and VOSviewer, among other processing tools. Results/Discussion. 1,779 publications were found that met the inclusion criteria-more than 75% are open access and 61% are articles- The English language predominates (more than 90%). Eleven articles collect 65, 8% of the citations, and three journals account for 65, 2% of the citations. The US stands out with 18% of the authors, the rest of the countries have less than 10%, even though Italy and China stick out. Collaborations between countries are dynamic with six different groups of alliances of researchers throughout the world. Regarding the specific topic discussed, five base topics were found: risk factors, description of the disease, effects in different countries, curative drugs, and detection tests. Conclusions. Scientists have done their job to stop this global threat, creating and disseminating relevant knowledge;the decision-making powers have the say: it is in their hands to use or not the knowledge generated. Originality/Value. It has become clear that the assessment of scientific knowledge, especially in extreme circumstances and / or emergencies, could mean a great saving in resources, time and lives.
ABSTRACT
Objectives: The COVID-19 disease is a public health emergency of international importance and vaccination is considered the best tool against it. The objective of this study was to evaluate the possible adverse reactions to the vaccine against COVID-19 reported by workers at a tertiary hospital in Madrid. Making a description of the frequency, the presence in the technical sheet, the association with the history of infection by SARS-COV-2 and age. Methods: A retrospective descriptive study of the possible adverse reactions reported to the Occupational Risk Prevention Service of the hospital after the administration of the two doses of the vaccine for COVID-19 (Comirnaty®) was carried out in a sample of 8446 workers that received the first dose 1 and 8255 that received the second. A comparative analysis was performed by applying Pearson’s Chi-square test for qualitative variables and the Mann-Whitney test for quantitative variables. Results: The subjects who reported adverse reactions were 207 after dose 1 (2.45% of total vaccinated) and 397 after dose 2 (4.80% of total vaccinated). 76.8% were older than 55 years (dose 1) and 15.9% with dose 2. 57% had symptoms that were already described in the technical data sheet (dose 1) and 70.5% with dose 2. 50.7% had been previously diagnosed with COVID-19 (dose 1) and 30.5% with dose 2. Conclusions: The adverse reactions reported in our study have been mild or moderate, coinciding with the studies consulted. Adverse reactions were more frequent after the second dose. Among the workers who reported adverse reactions, there were more with a history of COVID-19, especially after the first dose. The reactions produced after vaccination and their causal relationship with it should continue to be studied. © 2021, Accion Medica S.A.. All rights reserved.